Amcetyl 600 mg

Amcetyl 600 mg is a prescription-grade acetylcysteine powder for oral solution. It’s an effective mucolytic for respiratory conditions and a vital life-saving treatment in acetaminophen overdose due to its liver-protective action. Its use should always follow medical guidelines to ensure correct dosing and monitor for side effects like bronchospasm or allergic reactions.

Primary uses:

• Mucolytic therapy: Helps thin and loosen thick mucus in respiratory conditions like chronic bronchitis, COPD, cystic fibrosis, acute respiratory infections, and sinusitis

• Acetaminophen overdose antidote: Replenishes glutathione to reduce liver damage in overdoses.

• Typical dosage:

  • For mucus clearance: 600 mg once or twice daily, based on clinical guidance.

  • For overdose: High-dose regimens (e.g., 140 mg/kg initially then maintenance doses per protocol) under medical supervision.

• Mechanism of action: Breaks disulfide bonds in mucoproteins to reduce mucus viscosity and boosts antioxidant activity by increasing glutathione production.

• Common side effects: Nausea, vomiting, abdominal discomfort, rash; may trigger bronchospasm in asthma patients; hypersensitivity reactions are rare.

• Precautions:

  • Use with caution in asthma due to risk of bronchospasm.

  • Avoid in patients with GI ulcers or known hypersensitivity.

  • Monitor patients when using as an antidote, especially in overdose cases under clinical supervision.