LACTULOSE Avolac 120 mL
LACTULOSE Avolac 120 mL
Avolac 120 mL – Lactulose Oral Solution (3.35 g/5 mL)
What it is:
An osmotic laxative containing lactulose USP (3.35 g per 5 mL), sold as a syrup in a 120 mL bottle.
Uses:
-
Chronic constipation: Draws water into the colon to soften stools and stimulate bowel movements.
-
Hepatic encephalopathy / hyperammonemia: Reduces blood ammonia by acidifying the gut and trapping ammonia as ammonium, helping with brain symptoms in liver disease.
Onset of action: Typically works within 6–8 hours; best taken at bedtime.
Dosage Guide (Adapted from standard lactulose regimens):
| Indication | Adults | Children (5–17 y) |
|---|---|---|
| Constipation | 15 mL, twice daily (start); up to 60 mL once daily | 5–20 mL twice daily lifeplusmm.com+7nhs.uk+7arogga.com+7 |
| Hepatic encephalopathy | 30–50 mL, 3× daily; titrate to produce 2–3 soft stools/day | Use pediatric dosing accordingly |
Side Effects & Precautions
-
Common: Gas, bloating, abdominal cramps, diarrhea (if overdosed). aristopharma.com+1arogga.com+1
-
Potential issues: Electrolyte imbalance (low potassium), cautious use in patients with galactosemia, lactose intolerance, intestinal obstruction, or heart-gastrointestinal interactions. lifeplusmm.com+7aristopharma.com+7epharma.com.bd+7
-
Drug interactions: High doses may intensify effects of cardiac glycosides; some medications (e.g., mesalazine, antacids, neomycin) may interact.
Avolac 120 mL – Lactulose Oral Solution (3.35 g/5 mL)
What it is:
An osmotic laxative containing lactulose USP (3.35 g per 5 mL), sold as a syrup in a 120 mL bottle.
Uses:
-
Chronic constipation: Draws water into the colon to soften stools and stimulate bowel movements.
-
Hepatic encephalopathy / hyperammonemia: Reduces blood ammonia by acidifying the gut and trapping ammonia as ammonium, helping with brain symptoms in liver disease.
Onset of action: Typically works within 6–8 hours; best taken at bedtime.
Dosage Guide (Adapted from standard lactulose regimens):
| Indication | Adults | Children (5–17 y) |
|---|---|---|
| Constipation | 15 mL, twice daily (start); up to 60 mL once daily | 5–20 mL twice daily lifeplusmm.com+7nhs.uk+7arogga.com+7 |
| Hepatic encephalopathy | 30–50 mL, 3× daily; titrate to produce 2–3 soft stools/day | Use pediatric dosing accordingly |
Side Effects & Precautions
-
Common: Gas, bloating, abdominal cramps, diarrhea (if overdosed). aristopharma.com+1arogga.com+1
-
Potential issues: Electrolyte imbalance (low potassium), cautious use in patients with galactosemia, lactose intolerance, intestinal obstruction, or heart-gastrointestinal interactions. lifeplusmm.com+7aristopharma.com+7epharma.com.bd+7
-
Drug interactions: High doses may intensify effects of cardiac glycosides; some medications (e.g., mesalazine, antacids, neomycin) may interact.
